Antimicrobial Resistance in Staphylococcus
Moving in Journal of bacteriology, bioRxiv, Applied and environmental microbiology, Communications Biology, Gastroenterology, medRxiv, Virulence, Cell Reports.
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Latest in Antimicrobial Resistance in Staphylococcus
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S. aureus grown in milk shows 10-fold higher resistance to reactive oxygen species and increased antimicrobial tolerance compared to serum-grown bacteria.
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Lacticaseibacillus rhamnosus GG boosts gefitinib efficacy by 40% and reduces gastrointestinal and hepatic toxicity in non-small cell lung cancer models.
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A rapid sphingomyelin-dependent entry pathway in S. aureus alters intracellular fate, influencing bacterial replication and host cell death within minutes of contact.
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MbcS, a refunctionalized acyl-CoA synthetase in Staphylococcus aureus, provides a significant fitness advantage during intra-species competition under nutrient-limited conditions.
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Polyunsaturated fatty acids effectively kill glycolytic Staphylococcus aureus strains, including persisters and small colony variants, by inducing lipid peroxidation.
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C. difficile assembles a unique divisome complex in three phases, with PBP1 replacing FtsW-FtsI in septal peptidoglycan synthesis, highlighting a distinct bacterial division mechanism.
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TrbA binds and locks KorB, a DNA-sliding clamp, to repress transcription on multi-drug resistance plasmids, revealing a conserved clamp-locking mechanism involving multiple regulators.
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Loss of YqeK in Staphylococcus aureus causes a 1,000-fold increase in Ap 4 N levels and impairs stress resistance and virulence gene expression.
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Candida albicans reprograms Staphylococcus aureus glycolytic pathways, increasing its virulence by 2- to 3-fold in glucose-rich environments.
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The G2019S mutation in LRRK2 enhances NADPH oxidase-2 activity in neutrophils, improving bacterial infection control in mice by 2- to 3-fold.
Fibrin barriers in S. aureus staphylococcal communities restrict vancomycin penetration by over 50% and alter bacterial gene expression profiles.
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