The abstract is read at the publisher; the summary is JClub's.
MdMYB1R1 is strongly induced by Valsa mali infection in apple and functions as a nuclear transcriptional activator that enhances resistance to woody fungal trunk pathogens.
- Why it matters: Trunk diseases from woody pathogens threaten global apple production, yet the molecular regulators of host resistance are not well defined.
- What they did: Using TMT-based quantitative proteomics, the study identified 904 differentially expressed proteins in apple twig tissues after V. mali inoculation, then tested MdMYB1R1 localization and function via transient and stable overexpression and RNAi.
- The result: MdMYB1R1 overexpression increased ROS and MAPK signaling and improved resistance to Sclerotinia sclerotiorum, V. mali, and Botryosphaeria dothidea, while silencing reduced tolerance; DAP-seq, Y1H, EMSA, and reporter assays showed direct activation of MdMAPKKK18.
The findingWhy it mattersWhat they didThe result
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