The abstract is read at the publisher; the summary is JClub's.
In 12 insulin-treated adults with chronic intestinal failure on nocturnal cyclic parenteral nutrition, CGM-guided insulin optimization reduced time >250 mg/dL from 27% to 17%.
- Why it matters: Glucose control and nutrition can be difficult to balance during long-term nocturnal PN, and insulin regimens may not be optimized for real-time glycemic patterns.
- What they did: In a prospective single-center 30-day before-and-after study, participants underwent CGM assessment and then diabetologist-led insulin optimization guided by CGM data.
- The result: After intervention, time in range rose from 44% to 59% with no increase in hypoglycemia; HbA1c fell by -0.7%, glycosuria resolved in all affected patients, and malnutrition improved in 8 of 11.
The findingWhy it mattersWhat they didThe result
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