A serum thyroid hormone metabolite test for molecular diagnostic evaluation of thyroid nodules.

Cell Research · 1 Oct 2026 · Letter · Open access

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Kinetics of Re-differentiation with Short-Course Dabrafenib and Trametinib in Patients with Radioiodine-Refractory Thyroid Cancer.
Clinical Cancer Research · 9 Nov 2026 · Journal Article
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Short-course dabrafenib plus trametinib restored iodine uptake within 2 weeks in 6 of 9 (67%) radioiodine-treated patients with MAPK-driven radioiodine-refractory thyroid carcinoma.
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Familial medullary thyroid carcinoma secondary to an SLC30A9 intragenic deletion and translation reinitiation
medRxiv · 26 Oct 2026 · Preprint
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A novel heterozygous 40kb intragenic SLC30A9 deletion segregates with RET-negative familial medullary thyroid carcinoma in 21 affected individuals and yields truncated proteins.
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https://jclub.com.au/a/10.64898/2026.02.26.26346165
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RET-driven osteoprotegerin expression links medullary thyroid cancer to osteoblastic bone metastases.
Cell Reports Medicine · 15 Sept 2026 · Journal Article
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Activated RET signaling in patient-derived medullary thyroid cancer cells is linked to increased osteoprotegerin (OPG) expression, reduced osteoclast differentiation, and osteoblastic bone lesions in mouse femurs.
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https://jclub.com.au/a/42660113
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A serum thyroid hormone metabolite test for molecular diagnostic evaluation of thyroid nodules.

Related in JClub

Kinetics of Re-differentiation with Short-Course Dabrafenib and Trametinib in Patients with Radioiodine-Refractory Thyroid Cancer.

Familial medullary thyroid carcinoma secondary to an SLC30A9 intragenic deletion and translation reinitiation

RET-driven osteoprotegerin expression links medullary thyroid cancer to osteoblastic bone metastases.

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