Short-Lived Hyperglycaemia Contributes to Continuous Glucose Monitoring Metrics Used for Therapeutic Decision-Making

In a single-centre cohort of 135 paediatric type 1 diabetes patients, 18.5% of hyperglycaemic episodes met daytime short-lived hyperglycaemia criteria, shifting CGM metrics.

• Why it matters: CGM summaries like time in range and median glucose do not separate brief from sustained hyperglycaemia, potentially masking clinically relevant patterns.
• What they did: Using 5-minute CGM data from 2025–2026 with ≥70% coverage and a 45-day window, the study identified SLH as 10–60 minute episodes between normoglycaemia, then estimated metric effects by replacing SLH with plausible trajectories.
• The result: Removing daytime SLH increased daytime TIR by 1.74 percentage points (95% CI 1.59–1.89) and lowered daytime median glucose by 0.18 mmol/L (95% CI 0.17–0.20), with up to 1.30 mmol/L (95% CI 1.21–1.38) profile divergence near meals.

AI summary of the abstract · may contain errors · not medical advice · read the paper.