Rapid switching of in-phase and anti-phase interhemispheric rhythms within a single theta cycle: a mechanistic explanation

RSG recordings show gamma (30–80 Hz) is in-phase across hemispheres while splines (100–160 Hz) are anti-phase, switching within a single theta cycle (~8 Hz).

• Why it matters: Understanding how interhemispheric phase relationships emerge in RSG is needed to explain how memory and spatial navigation rhythms are coordinated across the two hemispheres.
• What they did: Numerical bifurcation analysis of next-generation neural mass models links within-hemisphere gamma/spline alternation to PING versus ING switching driven by theta-frequency input to inhibitory neurons.
• The result: Canonical delay-coupled two-module interhemispheric circuits reproduce the experimental cross-spectral statistics and analytical threshold-linear results predict phase patterning from the ratio of cross-hemispheric delay to local inhibitory delay.

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