The abstract is read at the publisher; the summary is JClub's.
A decade-long canine rabies virus epidemic in Arequipa, Peru is dominated by one lineage introduced around 2012, circulating for ~3 years before detection.
- Why it matters: Persistent urban foci block elimination, but micro-scale processes sustaining dog-mediated transmission and the surveillance gaps enabling cryptic spread remain unclear.
- What they did: The study combined 133 newly generated whole genomes with existing data to build a comprehensive canine RABV dataset in Latin America, then used whole-genome-informed phylogenetic, phylodynamic, and landscape analyses.
- The result: Only 1–2% of infections are routinely detected, and transmission is highly structured in densely populated, socioeconomically deprived areas shaped by roads and dry water channels, with one regional introduction sustaining spread.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.