Research area · week to 3 Oct 2026

Mental Health Research Topics

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Impact of Connectivity Granularity: A Comparison of ROI and Network-Level Approaches for Early Schizophrenia Classification
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.30.679496
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Directed effective connectivity between the SCN-containing hypothalamus and pineal gland varies by chronotype in bipolar disorder
medRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.26363889
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The Network Landscape of Non-Clinical Eating Behaviors in India
medRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.19.26348826
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Divergence in neurodivergent brains: mapping the relationship between developmental trajectories in functional connectivity and clinical outcomes
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.23.753857
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A self without a "we": Individuals with Borderline personality disorder show signatures of disrupted social basis functions
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.21.752665
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Weaker functional segregation of the sensory and default mode networks in trauma-related intrusive memories
medRxiv · 23 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.18.26363166
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Bullying, Psychosis-Like Experiences, and Functional Network Connectivity in Adolescents
medRxiv · 21 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.04.26345538
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Specific Sensitivity to Rare and Extreme Events: Quasi-Complete Black Swan Avoidance vs Partial Jackpot Seeking in Rat Decision-Making
bioRxiv · 19 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2021.11.01.466806
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Severity of Depression and Anxiety Symptoms is Reflected in Physiological and Behavioral Metrics Collected from a Consumer-Grade Wearable Ring
medRxiv · 16 Sept 2026 · Preprint
Severity of depression and anxiety correlates with measurable physiological and behavioral changes detected by a consumer-grade wearable ring, especially in moderate-to-severe cases.
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https://jclub.com.au/a/10.64898/2026.02.06.26345566
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Longitudinal associations between depressive symptoms and brain structure across late childhood and adolescence: A panel network analysis study
medRxiv · 4 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.24.26349162
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Brain cognition gaps reveal associations with dopamine and factors related to brain health through artificial intelligence prediction of functional connectome.
eLife · 2 Sept 2026 · Journal Article
Deep learning reveals that brain connectomes during tasks, especially movie-watching, predict individual cognitive differences with up to 80% accuracy in Homo sapiens.
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https://jclub.com.au/a/42684829
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NExON-Bayes: a Bayesian approach to network estimation informed by ordinal covariates.
Bioinformatics · 31 Aug 2026 · Journal Article
NExON-Bayes improves network estimation in heterogeneous biomedical data by integrating ordinal covariates, achieving higher accuracy than existing methods in high-dimensional settings.
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https://jclub.com.au/a/42233294
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Comparative Evaluation of rs-fMRI Representations for Differentiating Schizophrenia and Bipolar Disorder with Psychosis
medRxiv · 31 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.16.26355608
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Protein-protein interaction network architecture of human polygenic traits reveals domain-spanning connectivity and evolutionary pressures.
Genome Biology · 27 Aug 2026 · Journal Article
Genes linked to human polygenic traits show significantly higher connectivity in protein-protein interaction networks, with 4,756 phenotypes analyzed revealing key patterns.
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https://jclub.com.au/a/42665836
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A Computational Toolkit for Designing and Analysing Repeated Binary Choice Experiments
bioRxiv · 21 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.21.700416
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A multistable slow-fast model of affective state switching under circadian drive
bioRxiv · 20 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.11.705337
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Metabolic brain networks switch between a sparsely connected baseline and highly integrated states to support cognition
bioRxiv · 19 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.17.695042
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Epigenetic Aging in Monozygotic Twins Exposed to Psychosocial Adversity Suggests Sex-Specific, Contextual Outcomes
medRxiv · 19 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.28.26345032
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Clinically Grounded AI-Scribing in Psychotherapy: Benchmarking LLMs Against Expert Documentation in the iCARE Framework
medRxiv · 19 Aug 2026 · Preprint
GPT-4o-mini achieved the highest overall scores among 11 LLMs in generating clinically valid psychotherapy notes using the iCARE framework, with Gemini Pro excelling in interpretative tasks.
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https://jclub.com.au/a/10.1101/2025.06.25.25330252
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Untargeted plasma proteomics and clinical phenotypes in adolescent depression
medRxiv · 17 Aug 2026 · Preprint
Adolescent depression is linked to 308 plasma proteins involved in immune, metabolic, and extracellular matrix pathways, revealing shared biological signatures across clinical phenotypes.
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https://jclub.com.au/a/10.64898/2026.07.06.26356404
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Recurrent Physical Contact Network Relevant for Epidemic Spreading
medRxiv · 12 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.08.26350390
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Temporal stability of functional network configurations and its relationship to cognition and psychopathology in early psychoses
bioRxiv · 12 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.06.697919
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Distinct cortical profiles underlie the common reportability of thought-free experiences
bioRxiv · 11 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.14.681984
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Mood computational mechanisms underlying increased risk behavior in adolescent suicidal patients.
eLife · 7 Aug 2026 · Journal Article
Adolescent suicidal patients with suicidal thoughts exhibit a significant increase in risk-taking behavior driven by heightened approach tendencies and reduced reward sensitivity.
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https://jclub.com.au/a/42565458
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Mind the gap: quantifying individual-population gap in depressive symptom dynamics through energy landscapes
bioRxiv · 7 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.20.726729
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