ECLIPSE uncovers 120,985 dark proteins in the ESKAPE pathogens' proteomes, revealing conserved, structurally characterized targets for combating antimicrobial resistance.
- 1 cites
Machine Learning in Bioinformatics
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SynthIDBio enables function-preserving watermarking of AI-generated proteins with near-perfect detection accuracy, ensuring provenance in biological engineering.
- Open access
- 1 cites
A machine-learning framework predicts strain-level phage-host interactions across diverse bacteria with AUROC up to 0.94, independent of phylogenetic constraints.
- Open access
MS Andrea directly identifies and scores combinatorial peptide modifications, detecting up to four modifications per peptide with higher accuracy than existing tools.
- Open access
FORGE accurately recovers 64.6% of native nucleotides from RNA tertiary structure geometry, surpassing simpler controls and revealing residue-level information.
Pinal, a 16-billion-parameter model, translates natural language into diverse, functional proteins, with all four designed proteins demonstrating activity and enhanced performance.
- Open access
- 14 cites
HSTXGB achieves significantly better performance than eight state-of-the-art methods in inferring gene regulatory networks from time-course data, with improved accuracy demonstrated on multiple datasets.
- Open access
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