Polyamine Metabolism and Applications
Moving in bioRxiv, Plant Physiology and Biochemistry, Biotechnology advances, Cancer Research, Genome Medicine, Journal of Experimental Botany, mBio, Nature Chemical Biology.
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Conserved chemoresistance across cancers is driven by a proliferative, MYC-regulated tumor state involving SRM, with over 70% of resistant cells showing elevated cell cycle activity.
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Loss of eIF4G2 accelerates pancreatic cancer progression, metastasis, and basal-like tumor features, highlighting its role as a critical translational checkpoint.
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