Detection of molecular residual disease via circulating tumor DNA identifies high recurrence risk in resectable solid tumor patients, enabling more efficient clinical trials.
Radiopharmaceutical Chemistry and Applications
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POLE exonuclease deficiency causes synthetic lethality in highly aneuploid cancer cells, revealing a potential targeted therapy approach.
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Non-invasive imaging of cancer hallmarks enables real-time monitoring and stratification of tumors, with some techniques already impacting clinical treatment decisions.
-based CD45 radioimmunotherapy achieves effective, targeted conditioning with minimal non-hematologic toxicity in primates, enabling high-efficiency gene-edited HSPC engraftment.
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