Research area · week to 3 Oct 2026

Health Systems, Economic Evaluations, Quality of Life

Moving in medRxiv, New England Journal of Medicine, Environmental research, Journal of hepatology, Nature Biotechnology, Nature Genetics, The Lancet, The Lancet Oncology.

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Development and validation of early warning scores predicting 24-hour mortality addressing intercurrent medical interventions: a multi-centre retrospective cohort study of 2,08 million hospital encounters
medRxiv · 1 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.12.25337794
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Beyond mortality: A multi-outcome assessment of health economic benefits from air pollution control in China.
Environmental research · 1 Oct 2026 · Journal Article
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https://jclub.com.au/a/42624321
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Joint Clinical Assessments - A New Chapter in European Pharmaceutical Policy.
New England Journal of Medicine · 1 Oct 2026 · Journal Article
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https://jclub.com.au/a/42804610
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Balancing benefits, costs, and harms: policy implications of expanding cancer susceptibility testing from genetics clinics to the general population.
The Lancet Oncology · 1 Oct 2026 · Review
Expanding cancer susceptibility testing to the general population requires careful evaluation of clinical and public health benefits, with evidence supporting its use mainly for well-established genes.
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https://jclub.com.au/a/42790443
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A Generalizable, Governance-Embedded Pathway for Assessing Patient-Level Opportunities for Genetic Medicines
medRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.22.26363712
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High-Throughput Observational Evidence Generation Using Linked Electronic Health Record and Claims Data
medRxiv · 18 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.07.26350300
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The Future of the USPSTF and Evidence-Based Recommendations.
New England Journal of Medicine · 10 Sept 2026 · Journal Article
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https://jclub.com.au/a/42708473
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Applying the FDA's plausible mechanism guidance across the rare disease landscape.
Nature Genetics · 9 Sept 2026 · Journal Article
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https://jclub.com.au/a/42717240
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Lessons from drug revenue life cycles: distributions across modalities and therapeutic areas.
Nature Biotechnology · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42613383
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Which outcomes of pharmacist-involved services are measured well enough to support decisions? A systematic review, meta-analysis, and evidence map of 266 randomised trials in China
medRxiv · 31 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.07.25.24310734
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Regulation-Driven Variation in Utilization and Cost of B-Cell Depleting Therapies for Multiple Sclerosis: A Cross-National Study
medRxiv · 22 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.19.26360842
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A precision health approach to medication management in neurodevelopmental conditions: a model development and validation study using four international cohorts
medRxiv · 17 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.03.12.25323683
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Can the CIRI model reliably predict cACLD decompensation for clinical adoption?
Journal of hepatology · 13 Aug 2026 · Letter
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https://jclub.com.au/a/42595142
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Advancing the relevance of clinical trials for older patients.
The Lancet · 8 Aug 2026 · Review
Implementing inclusive clinical trial strategies can improve relevance for older patients, with successful approaches now demonstrating feasibility and real-world applicability.
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