Early-onset colorectal cancer (EOCRC) cases under age 50 are rising globally, with lifestyle and early-life factors contributing to the increasing burden.
Colorectal Cancer Surgical Treatments
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Having 5 to 10 nonadvanced adenomas significantly increases the risk of advanced colorectal neoplasm, with a 10.1% 5-year incidence, highlighting the need for tailored surveillance.
A blood-based assay detects colorectal cancer and advanced adenomas with 95% accuracy, showing 91% sensitivity for cancers and 81% for advanced adenomas in a multicentre study.
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Patient navigation and mailed FIT outreach significantly increase colorectal cancer screening uptake, especially in populations with low baseline rates, with risk ratios of 1.58 and 1.36 respectively.
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