Research area · week to 3 Oct 2026

Sepsis Diagnosis and Treatment

Moving in medRxiv, New England Journal of Medicine, bioRxiv, Gut, Gastroenterology, JAMA, Journal of hepatology, mSystems.

Moved this week: 0

Rebuilt 3 October 2026 at 4:06 pm AEST

Moved this week

Everything that moved →

Nothing in this area has moved yet this week.

Latest in Sepsis Diagnosis and Treatment

Newest first · last 60 days

Serum proteomics in newborns reveals a multi-pathway molecular panel for neonatal sepsis, encompassing pathogen sensing, leukocyte recruitment, and endothelial injury.
bioRxiv · 1 Oct 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.27.728097
Open in JClub
Deciphering sepsis molecular subtypes using large-scale data to identify subtype-specific drug repurposing
bioRxiv · 28 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.03.28.714506
Open in JClub
Toward personalized and longitudinal antibiograms--a proof-of-concept for in vivo assessments of immunological-antibiotic-bacterial interactions
medRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.24.26363858
Open in JClub
The impact of the SYNTAX score on the incidence of in-hospital cardiac arrest in patients with acute coronary syndrome undergoing percutaneous coronary intervention: a retrospective cohort study
medRxiv · 25 Sept 2026 · Preprint
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.23.26363831
Open in JClub
Characteristics associated with culture-positivity versus antibiotic administration in patients with cirrhosis on ICU admission: a retrospective cohort study in 5 hospitals.
medRxiv · 24 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.22.26363729
Open in JClub
Empirical antibacterial use, escalation, microbiological profile, and outcomes in febrile neutropenia: An ambispective observational study
medRxiv · 23 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.09.22.26363666
Open in JClub
Pre-illness Clonal Hematopoiesis of Indeterminate Potential is Associated with Increased Morbidity and Mortality in Sepsis
medRxiv · 17 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.04.14.26350864
Open in JClub
Sodium Bicarbonate for Critically Ill Adults with Metabolic Acidosis and Shock.
New England Journal of Medicine · 17 Sept 2026 · Randomized Controlled Trial
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42283370
Open in JClub
The Causal Artificial Intelligence Clinician for early haemodynamic management of septic shock in ICU
medRxiv · 14 Sept 2026 · Preprint
A causal AI model for early septic shock management achieved comparable survival prediction with fewer variables, guiding fluid and vasopressor therapy in ICU patients.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.07.06.26357375
Open in JClub
Cell-composition sensitivity of pooled whole-blood DNA methylation profiling in sepsis using the Infinium MethylationEPIC v2.0 array and SeSAMe
medRxiv · 11 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.29.26354469
Open in JClub
When Fear Became the Barrier to Care - Lessons of a Clinical Rapid Response during Operation Metro Surge.
New England Journal of Medicine · 10 Sept 2026 · Journal Article
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42708471
Open in JClub
Lactate Cut-offs for 28-Day Mortality in Septic Shock
medRxiv · 9 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.02.08.26345840
Open in JClub
Pharmacological trials of early intervention in predicted severe acute pancreatitis: implications for therapeutic window and core outcome set.
Gut · 7 Sept 2026 · Letter
Read the brief in JClub
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/41161710
Open in JClub
Discovery and validation of serum metabolic signature of neonatal sepsis
medRxiv · 4 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2024.03.07.24303587
Open in JClub
Serum IL-6, IL-10, TNF-α and IFN-γ bio-signature for neonatal sepsis diagnosis and treatment outcome
medRxiv · 4 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.02.12.25320841
Open in JClub
Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock.
New England Journal of Medicine · 3 Sept 2026 · Randomized Controlled Trial
Balanced crystalloid fluid does not significantly reduce adverse kidney events compared to 0.9% saline in children with septic shock, with event rates of 3.4% versus 3.0%.
- Open access
- 4 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42028918
Open in JClub
PRE-CISE: A PRE-calibration Coverage, Identifiability, and SEnsitivity analysis workflow to streamline model calibration
medRxiv · 3 Sept 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.02.27.26346591
Open in JClub
Reply.
Gastroenterology · 1 Sept 2026 · Letter
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42217553
Open in JClub
The LIBERATE Internal Randomized Controlled Pilot Trial: Adjunctive midodrine therapy for early liberation from vasopressor support in critically ill patients
medRxiv · 26 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.07.31.25332174
Open in JClub
Quantifying the Optimism of Naive Cross-Validation for Binary Outcome Prediction with Repeated-Measures Predictors: A Simulation Study and Clinical Illustration
medRxiv · 26 Aug 2026 · Preprint
Read the brief in JClub
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.05.27.26354222
Open in JClub
Sodium Bicarbonate for In-Hospital Cardiac Arrest: A Randomized Clinical Trial.
JAMA · 25 Aug 2026 · Equivalence Trial
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42273960
Open in JClub
Replication of protein associations is not external validation of a fixed mortality score.
Gut · 24 Aug 2026 · Letter
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42637527
Open in JClub
PRAM: post-hoc retrieval augmentation adapts intensive care prediction models without retraining and can be shared across hospitals
medRxiv · 21 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.04.03.26350132
Open in JClub
Diagnostic performance and antibiotic impact of droplet digital PCR in suspected sepsis: the PROGRESS trial.
Nature Communications · 20 Aug 2026 · Randomized Controlled Trial
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42749736
Open in JClub
Higher abundance of Faecalibacterium prausnitzii in the gut microbiome is associated with a lower risk of sepsis development among 6,372 individuals followed for 20 years.
mSystems · 18 Aug 2026 · Journal Article
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42429614
Open in JClub
Non-selective beta-blockers in cirrhosis and AKI: Time to reconsider routine withdrawal?
Journal of hepatology · 13 Aug 2026 · Editorial
Read the brief in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42595136
Open in JClub
Generalizing intensive care AI across time scales in resource-limited settings
medRxiv · 12 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.04.23.26351588
Open in JClub
Circulating Metabolites Associated with Prothrombin Time and Activated Clotting Time in Children with Congenital Heart Disease: An Untargeted Metabolomics Study
medRxiv · 9 Aug 2026 · Preprint
Read the brief in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.1101/2025.11.07.25339794
Open in JClub
Conservative Oxygen for Unresponsive Patients after Cardiac Arrest.
New England Journal of Medicine · 6 Aug 2026 · Randomized Controlled Trial
Conservative oxygen therapy does not improve 180-day survival with favorable functional outcomes compared to liberal oxygen in post-cardiac arrest ICU patients.
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42267831
Open in JClub

Follow this area in the app

Journals this month

All journals →

Moving areas, week to 3 Oct 2026

All research areas →

Read

Moved this week

Latest in Sepsis Diagnosis and Treatment

Browse JClub