Single-cell genomics reveals diverse pathogenic immune cell subsets in rheumatoid arthritis, paving the way for targeted therapies.
Rheumatoid Arthritis Research and Therapies
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Selective targeting of IL-6 trans-signalling pathway offers potential for safer, more precise therapies, as it accounts for distinct roles in disease and homeostasis.
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Duvakitug demonstrated a significant endoscopic response in 48% of patients with Crohn's disease, with the 900 mg dose exceeding placebo response rates in a phase 2b trial.
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Secukinumab significantly increases remission rates and reduces glucocorticoid use in relapsed polymyalgia rheumatica patients compared to placebo.
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