Human stem cell neuroscience.

Stem-cell-based models are expanding access to human neural biology by enabling generation, assembly, probing, and perturbation of neural cells and circuits.

• Why it matters: Neuroscience has struggled to study the most relevant human biology because it has been difficult to access directly.
• What they did: The field uses stem-cell approaches such as organoids and assembloids, and this issue of Neuron reviews and comments on the state of the emerging area.
• The result: These models help define “stem cell neuroscience,” supporting clearer characterization of neural cells and circuits and guiding future experimental directions.

AI summary of the abstract · may contain errors · not medical advice · read the paper.