Plant Physiol BiochemJClub
The UDP-glucose 4-epimerase GhUGE2 positively regulates drought tolerance in upland cotton (Gossypium hirsutum).
Plant Physiology and Biochemistry · · Journal Article · Open access
Li, Zhang + more
Abstract ↗AI summary
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Overexpressing GhUGE2 in upland cotton (Gossypium hirsutum) enhances drought tolerance, lowering water loss, ROS accumulation, and lipid peroxidation while boosting antioxidant enzymes.
- Why it matters: Drought frequently limits cotton growth, yet the role of UDP-glucose 4-epimerase in cotton drought tolerance is unclear, limiting targeted improvement strategies.
- What they did: The cotton UGE gene family was characterized and GhUGE2 selected; its promoter was found to contain stress-responsive cis-elements, then GhUGE2 was overexpressed or silenced and drought phenotypes, ROS, lipid peroxidation, and antioxidant activities were measured.
- The result: GhUGE2 silencing increased ROS accumulation, reduced antioxidant capacity, impaired water retention, and increased drought sensitivity, and transcriptome enrichment linked GhUGE2 effects to hormone signaling, MAPK pathways, and drought-responsive transcription.
The findingWhy it mattersWhat they didThe result
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