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Author Correction: Programmable DNA pyrimidine base editing via engineered uracil-DNA glycosylase.

Nature Communications · 6 Nov 2026 · Published Erratum · Open access

Yi, Zhang + more

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An engineered, compact Cas12m variant for multiplexed gene activation in vivo.
Nature Biotechnology · 28 Oct 2026 · Journal Article
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An engineered denCas12m enables smCRISPRa to process a multi-gRNA array into functional guides in vivo, supporting up to eight crRNAs for activating six genes from one AAV vector in mice.
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RNA-Triggered Chromatin Shredding Hits Cancer's Hardest Targets.
Cancer Discovery · 23 June 2026 · News
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In mouse tumor models, activating Cas12a2 by a target transcript enables RNA-triggered chromatin shredding that selectively eliminates cells with mutations in TP53, MYC, and other hard-to-drug cancer genes.
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Prime editing enables drug-controllable T-cell therapies with clinical immunosuppression.
Blood · 5 Nov 2026 · Journal Article
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Multiplex prime editing creates T cells with defined drug resistance, enabling selective in vivo expansion and rapid pharmacologic suppression in humanized mouse models under immunosuppression.
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