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Ca(2+) signature gates responsiveness to exogenous auxin in Arabidopsis roots.
Nature Communications · · Journal Article · Open access
Song, Baudon + more
Abstract ↗AI summary
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Optogenetically imposed cytosolic Ca2+ signatures in Arabidopsis thaliana roots suppress both membrane depolarization and auxin-triggered Ca2+ transients, with prolonged stimulation altering auxin-responsive transcription.
- Why it matters: Real-time mechanisms that tune auxin signaling during growth versus arrest, especially under stress, are not well understood.
- What they did: Using light-gated, Ca2+-permeable Channelrhodopsin 2 variant XXM2.0, the authors repeatedly and then persistently activated Ca2+ signals in root cells and measured auxin-evoked electrical and transcriptional responses.
- The result: Ca2+ stimulation reversibly inhibits root growth by suppressing cell division and elongation, and a candidate CaM7-CNGC14 module is identified as a likely mediator of Ca2+-dependent gating of auxin responsiveness and growth inhibition.
The findingWhy it mattersWhat they didThe result
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- Open access
- 2 cites