After 12 mo of DAPT following PCI in multivessel CAD, extended DAPT vs. aspirin alone reduced MACCE without increasing bleeding.

In multivessel coronary artery disease patients after PCI, extending dual antiplatelet therapy to 12 months reduced MACCE versus aspirin alone, without increasing bleeding.

• Why it matters: Optimal duration of DAPT after PCI in multivessel CAD is uncertain, especially balancing prevention of MACCE against bleeding risk.
• What they did: Patients received DAPT for 12 months after PCI, then were assigned to extended DAPT or aspirin alone; outcomes included MACCE and bleeding.
• The result: Extended DAPT lowered MACCE compared with aspirin alone and did not raise bleeding, supporting longer DAPT in this post-PCI multivessel CAD setting.

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