The abstract is read at the publisher; the summary is JClub's.
Pooled estimates from 86 population-based studies show infantile-onset epilepsies have a cumulative incidence of 236.0 per 100,000 live births, driven by DEEs.
- Why it matters: Global incidence and prevalence evidence for neonatal and infantile-onset epilepsies is fragmented, limiting understanding of worldwide burden and etiological profiles.
- What they did: The review searched PubMed, Embase, Web of Science, and Scopus through December 18, 2025, then pooled incidence, prevalence, and etiology using generalized linear mixed-model random-effects meta-analysis with subgroup analyses by country and region.
- The result: DEEs had the highest incidence at 67.7 per 100,000 live births, with infantile epileptic spasms syndrome at 31.6, while data were mostly from high-income countries in the European Region.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.