Haloxyfop-R-methyl resistance in Polypogon fugax: involvement of ABCG25 and ACCase gene overexpression.

Polypogon fugax population CZ-R shows 15.83-fold resistance to haloxyfop-R-methyl without target-site mutations, linked to ABCG25 and ACCase gene overexpression.

• Why it matters: Understanding resistance mechanisms in weeds like P. fugax is crucial for developing effective control strategies, especially as resistance to herbicides like ACCase inhibitors becomes more widespread.
• What they did: Researchers conducted dose-response assays, gene expression analyses, and heterologous overexpression experiments, revealing that resistance involves overexpression of ABCG25 and ACCase, not target mutations or herbicide degradation.
• The result: The study indicates that resistance is associated with both target gene overexpression and enhanced antioxidant responses, providing insights into complex non-target-site resistance mechanisms in grass weeds.