PEtab Select: Specification standard and supporting software for automated model selection.

PEtab Select standardizes model selection specification and supports billions of model alternatives, enabling efficient comparison in biological system modeling.

• Why it matters: Choosing relevant biological processes and models is crucial for understanding systems, but lacks standardized tools for defining and evaluating large model spaces, hindering progress.
• What they did: They developed PEtab Select, a new file format and software package built on the PEtab standard, supporting various model selection criteria and exploration methods, compatible with multiple workflows.
• The result: This standardization enhances flexibility, scalability, and interoperability in model selection, facilitating more comprehensive and reproducible analyses in systems biology research.