The digital map of homologous gene clusters across Poaceae species unveils the complex evolutionary trajectories of genes in Triticeae.

GoldMiner built a genus-level pangenomic map indexing half a million homologous gene clusters across 248 diploid genomes from 25 Poaceae species.

• Why it matters: Fine-scale gene evolutionary trajectories within local genomic contexts across genera are still poorly resolved, limiting understanding of how genome change supports adaptation.
• What they did: The tool uses homologous gene clusters as evolutionary units and performs hierarchical alignment of pangenomic HOCs; it also supports interactive exploration via waGOLD.
• The result: In Triticeae, newborn HOCs are strongly associated with stress response and defense, and two-thirds of Triticeae HOCs expanded, including NLR-containing clusters linked to disease resistance in wheat and barley.

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