From pressure to prognosis: establishing a common language for portal hypertension in advanced chronic liver disease.

Non-invasive tests can predict decompensation risk in advanced liver disease as accurately as HVPG, enabling personalized prognosis and management.

• Why it matters: Current risk assessment relies on static pressure measurements that do not capture individual disease trajectories, limiting timely intervention and patient understanding.
• What they did: The study reviews non-invasive tools like elastography, risk models such as ANTICIPATE, and blood scores, demonstrating their comparable accuracy to HVPG in predicting clinical decompensation.
• The result: Implementing these models allows continuous risk monitoring and may improve clinical decision-making, emphasizing standardized endpoints and outcome-based terminology to enhance patient care.