Rome V global epidemiology and validation survey: prevalence of disorders of gut-brain interaction and comparison with the Rome IV global epidemiology study.

The global prevalence of disorders of gut-brain interaction remains consistent at around 41% using Rome V criteria, confirming high worldwide burden.

• Why it matters: Understanding the epidemiology of DGBI is crucial for healthcare planning and resource allocation, yet previous data lacked validation across updated diagnostic standards.
• What they did: A population-based internet survey of 28,771 adults across 15 countries applied Rome V criteria and compared results with Rome IV data, analyzing demographic and clinical associations.
• The result: Prevalence rates were similar between Rome V and IV, with key disorders like functional dysphagia, functional dyspepsia, and IBS showing consistent rates, supporting the validity of these estimates globally.