Gut · 6 Aug 2026 · Journal Article · Open access

Impact of surveillance colonoscopy on colorectal cancer incidence and mortality in Lynch syndrome: a national observational cohort study of patients in the English NHS 2010-2022.

Huntley, Loong + more

Open access

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Comprehensive Genomic Analysis of Normal and Cancer Cells Elucidates the Elevated Mutational Burden in Cancer.
Cancer Research · 2 Oct 2026 · Journal Article
Cancers exhibit a four-fold higher mutation burden than normal tissues across five organs, driven by individual baseline mutation rate differences.
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https://jclub.com.au/a/42430563
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Mismatch Repair-Proficient Colorectal Cancer Can Evade Immune Surveillance through an Intrinsic Suppressive Program.
Cancer Discovery · 1 Oct 2026 · Journal Article
Mismatch repair-proficient Colorectal Cancer evades immune attack through intrinsic secretome-driven suppression, despite identical antigen presentation in 25 words.
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Nonadvanced Adenoma Number and Size as Predictors of Metachronous Advanced Colorectal Neoplasm: Implications for Surveillance Guidelines.
Gastroenterology · 1 Oct 2026 · Journal Article
Having 5 to 10 nonadvanced adenomas significantly increases the risk of advanced colorectal neoplasm, with a 10.1% 5-year incidence, highlighting the need for tailored surveillance.
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https://jclub.com.au/a/42142544
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