Dengue among febrile patients in Ghana: prevalence and facility-level variation in a multisite surveillance study

Dengue NS1 and/or IgM positivity was found in 6.95% of 2,936 febrile patients across six Ghanaian public facilities, with facility prevalence ranging from 3.88% to 12.32%.

• Why it matters: Limited laboratory testing in Ghana leaves dengue under-recognized, so clinicians and surveillance systems need evidence of where and in whom dengue is being detected.
• What they did: In cross-sectional multisite surveillance (Aug 2023–Jul 2025), consecutive febrile patients aged ≥1 year were tested by ELISA for NS1 and IgM, with NS1 positives confirmed by RT-PCR and serotyping.
• The result: Adjusted odds increased with age (aOR per five years 1.09; 95% CI 1.05–1.14), and RT-PCR detected dengue RNA in 8 NS1-positive samples, including DENV-1 (Bono East) and DENV-3 (Upper West).

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