bioRxivJClub
Reticulation-Aware Dissimilarities for Phylogenetic Networks
bioRxiv · · Preprint · Open access
Guang, Kessler + 3 more
Abstract ↗AI summary
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A new family of phylogenetic network dissimilarities separates reticulation disagreement from tree-like disagreement, yielding pseudometrics on rooted binary networks and metrics on binary level-1 networks.
- Why it matters: Existing network dissimilarities may not distinguish hybridization or horizontal gene transfer errors from tree-structure errors, limiting accurate comparison and summary of inferred phylogenetic networks.
- What they did: The authors introduce reticulation-aware measures, prove pseudometricity on rooted binary phylogenetic networks on a fixed taxon set, and show two instantiations become metrics on binary level-1 networks.
- The result: Empirical and calibration experiments show the measures stay sensitive to reticulation errors as network size increases and respond to changes in hybrid identity and parental placement, implemented in PhyNetPy.
The findingWhy it mattersWhat they didThe result
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