PROSPECTIVE COMPARISON OF OPTIMIZED COMPRESSED SENSING AND GRAPPA-ACCELERATED 3D-TOF-MRA FOR EVALUATION OF UNTREATED INTRACRANIAL ANEURYSMS AT 1.5 T: A NON-INFERIORITY STUDY

CS-accelerated 3D-TOF-MRA at 1.5T is non-inferior to GRAPPA-accelerated 3D-TOF for overall image quality in 25 patients with 32 untreated intracranial aneurysms, with 38.7% shorter scans.

• Why it matters: Long acquisition times limit routine 3D-TOF-MRA for intracranial aneurysm evaluation, and CS acceleration has been mainly studied at 3T rather than 1.5T.
• What they did: In a prospective single-center non-inferiority design, two blinded neuroradiologists compared CS (factor 7; 3:04 min) versus GRAPPA (factor 2; 5:00 min) using overall image quality as the primary endpoint and CNR, artifacts, and diameter measurements as secondary endpoints.
• The result: CS met non-inferiority for overall image quality (p <= .023) and preserved aneurysm diameter reliability (CS ICC 0.899–0.980; GRAPPA ICC 0.877–0.973; all p < .001), but ROI-based CNR was lower (median 169.6 vs 278.2) and interrater agreement for overall quality was low (ICC 0.241–0.262).

AI summary of the abstract · may contain errors · not medical advice · read the paper.