Stop-Flow Lithography Using Hydrodynamic Flow Resistance Regulation and Hydraulic Compliance Minimization for Size-Tunable Anisotropic Multilayered Microparticles Fabrication

A pneumatic-controlled stop-flow lithography platform enables rapid flow stopping for size-tunable anisotropic multilayered microparticles across 500, 250, and 100 m outlets by regulating hydrodynamic resistance and minimizing hydraulic compliance.

• Why it matters: Stop-flow lithography in multi-inlet setups is limited by slow stopping when high flow resistance and hydraulic compliance store extra fluid volume.
• What they did: The team modeled flow stopping as release of extra stored volume from hydraulic compliance, identifying PDMS inlet port deformation as the main source, then tuned tubing-to-outlet resistance and reduced PDMS membrane compliance using a glass support.
• The result: The strategies produce well-defined particle boundaries at short flow-stopping delay times while preserving multi-inlet flow profiles during stopping and transferring them into particle patterns.

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