Effect of Intensity Discretization on Radiomic Features in En Face EDI-OCT of Choroidal Nevi

Intensity discretization in en face EDI-OCT of stable choroidal nevi alters 77 radiomic features, with median occupied gray levels dropping from 54 at FBW 2 to five at FBW 25.

• Why it matters: Radiomic measurements depend on how intensities are binned, yet discretization effects in OCT choroidal lesion imaging are not well characterized, risking inconsistent feature selection.
• What they did: From 64 eyes, 93 original-domain radiomic features were extracted across 11 settings spanning FBW 2–64 and FBN 8–64, then evaluated using per-eye ICCs, ranking concordance, redundancy, overlap, and histogram entropy.
• The result: Observer reproducibility (median ICC 0.84–0.91) showed no clear setting differences, while rankings and feature sets changed; FBW 4 and FBN 32 retained at least 16 occupied gray levels in ~99% and 100% of observations, respectively.

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