Monocyte-derived galectin-1(hi) cells are essential for generating and maintaining lung tissue-resident memory CD8+ T cells after influenza infection, with over 4 months persistence.
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Galectins and Cancer Biology
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Galectin-1 drives monocyte hyperinflammation in myeloproliferative neoplasms, with Lgals1 ablation reducing disease features in mice.
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IL-16-driven signaling mediates resistance to BTK inhibitors and R-CHOP in B-cell lymphomas, with IL-16 upregulation observed in resistant cases.
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- 6 cites
Folding-mediated secretion using ProAla mutations yields highly pure bispecific antibodies with 100% correct pairing in IgG-like formats.
- Open access
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Large-scale glycomics datasets are revolutionizing understanding of glycan functions, with recent advances enabling extensive studies to uncover biological roles.
Galectin-3 enhances CaV1.2 channel activity and blood pressure, with blocking peptides reducing hypertension by over 35% in rat models.
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