Histone Deacetylase Inhibitors Research
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Latest in Histone Deacetylase Inhibitors Research
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ACLY palmitoylation driven by palmitic acid enhances macrophage histone acetylation, suppressing hepatocellular carcinoma progression by reprogramming the tumor microenvironment.
- Open access
Acetate inhibits esophageal squamous cell carcinoma growth by activating an ACSS2-dependent H2A.Z acetylation pathway, with low acetate and ACSS2 linked to poor prognosis.
- Open access
A small-molecule bivalent glue activates cell death in diffuse large B cell lymphoma by linking lysine acetyltransferases to oncogenic pathways, achieving targeted epigenetic reprogramming.
- Open access
- 13 cites
Lactate-α-ketoglutarate metabolic circuit in tumor-infiltrating Treg cells promotes tumor progression by inducing NK cell senescence, with GDH1 as a key driver.
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