Translumbosacral neuromodulation therapy with 2400 and 3600 magnetic pulses significantly reduces fecal incontinence episodes compared to sham, with responder rates up to 81.1%.
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Urinary Bladder and Prostate Research
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Low-frequency tibial neuromodulation (1 Hz) excites bladder activity and alters urge perception in humans, demonstrating a frequency-dependent effect on bladder control.
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Excessive epithelial mechanosensation via PIEZO1 increases glutamate-driven nerve growth, causing chronic bladder pain in infection models.
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ESR1+ neurons in the pontine micturition center precisely control bladder and urethral sphincter coordination with 100% reliability in mammals.
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