Research area · week to 3 Oct 2026

Glaucoma and retinal disorders

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Single-cell characterization of anterior segment development in the mouse reveals the cell types, pathways, and signals driving formation of the trabecular meshwork and Schlemm's canal.
eLife · 21 July 2026 · Journal Article
Single-cell transcriptomics of mouse anterior segment development reveals 130,000 cells and key pathways driving trabecular meshwork and Schlemm's canal formation.
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Transducin: an open-source pipeline recovering SNOMED-CT coded measurements from the undocumented Optopol .OPT and Zeiss Cirrus private-tag formats as DICOM Structured Reports
medRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.14.26357256
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Multimodal Prediction of Primary Open-Angle Glaucoma Using Polygenic Risk Scores and Clinical Features in a High-Risk African Ancestry Cohort
medRxiv · 21 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.27.25336797
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Surface Chemistry and Interfacial Biophysics of Meibum and Meibum--Benzalkonium Chloride Films: Implications for Tear Film Lipid Layer
bioRxiv · 14 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.13.731656
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Variant-to-gene mapping in ocular cell types identifies candidate effector genes for primary open-angle glaucoma
bioRxiv · 14 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.20.707051
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Endophenotype-Informed Polygenic Risk Stratification for Primary Open-Angle Glaucoma in individuals of African Ancestry
medRxiv · 28 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.29.25336758
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NAD boosting mediated by CD38 inhibition drives reversal of a pathological vicious cycle of intracrine activity and inflammation in eyelid meibomian gland dysfunction
bioRxiv · 24 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.08.704637
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Axial Length Matters: Scaling Effects in Retinal Fundus Image Analysis
medRxiv · 21 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.03.26347501
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Biologically Driven In Vivo Occlusion Design Provides a Reliable Experimental Glaucoma Mouse Model
bioRxiv · 21 Aug 2026 · Preprint
Viscobeads induce sustained ocular hypertension of 21.4 mm Hg for at least 8 weeks in mice, causing significant retinal ganglion cell loss and visual impairment.
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https://jclub.com.au/a/10.1101/2024.01.18.576306
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Modeling Retinal Ganglion Cell Degeneration from Longitudinal Intraocular Pressure Trajectories
bioRxiv · 18 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.09.743809
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Microsaccadic eye movement generation is sufficient to enhance peripheral visual sensitivity
bioRxiv · 9 Aug 2026 · Preprint
Microsaccades alone can enhance peripheral visual sensitivity across large eccentricities without attentional shifts in rhesus macaques.
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https://jclub.com.au/a/10.1101/2024.12.23.630151
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Multimodal Fusion of Circular Functional Data on High-resolution Neuroretinal Phenotypes
bioRxiv · 5 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.02.716157
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