Research area · week to 3 Oct 2026

Cardiac electrophysiology and arrhythmias

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Latest in Cardiac electrophysiology and arrhythmias

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Multimodal Integration of Ambulatory ECG and Clinical Features for Sudden Cardiac Death and Pump Failure Death Prediction
medRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.21.26351421
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Computational Framework for Identifying Ion Channel Mutation-Compensating Interventions
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.20.753002
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Endogenous subthreshold noise and PIP2 tune diastolic coherence across the intact sinoatrial node through stochastic resonance
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.18.752780
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Monte Carlo modeling of the formation and organization of ion channel clustering.
PLOS Computational Biology · 17 Sept 2026 · Journal Article
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https://jclub.com.au/a/42752396
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WNK-SPAK/OSR1 signaling pathway facilitates ictal activity via reduced neuronal chloride extrusion rate
bioRxiv · 14 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.10.731153
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Image-based deep learning for emergency electrocardiogram classification
medRxiv · 11 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.18.26355968
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Mathematical Modeling of Late-Stage LC Aggregation and Cardiac Injury Following Establishment of a Pathogenic Plasma-Cell Clone
bioRxiv · 6 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.30.685705
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Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias.
Nature Communications · 2 Sept 2026 · Journal Article
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https://jclub.com.au/a/42686760
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Heterogeneous Treatment Effects in HFpEF: Distinguishing Drug-Specific Response from Prognostic Phenotypes Across Randomized Trials
medRxiv · 28 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.06.26357251
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Characterization of an early-diverging KCNE potassium-channel auxiliary subunit in the jawless vertebrate lamprey.
eLife · 26 Aug 2026 · Journal Article
Lamprey KCNE0, an early-diverging KCNE family member, induces constitutive KCNQ1 activity, highlighting its unique role in vertebrate ion channel regulation.
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https://jclub.com.au/a/42647063
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Subcutaneous Defibrillator Implantation With or Without Defibrillation Test: The Primary Results of the Randomized PRAETORIAN-DFT Trial.
Circulation · 11 Aug 2026 · Randomized Controlled Trial
Omitting defibrillation testing guided by the PRAETORIAN score is noninferior, with a 1.7% failure rate, compared to testing in S-ICD implantation over 41 months.
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https://jclub.com.au/a/42033346
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Efficient and reproducible pipelines for spike sorting large-scale electrophysiology data.
eLife · 5 Aug 2026 · Journal Article
Parallelized spike sorting pipeline achieves faster, scalable, and reproducible analysis of large-scale electrophysiology data, outperforming previous algorithms like Kilosort2.5.
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https://jclub.com.au/a/42554034
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SLAy-ing oversplitting errors in high-density electrophysiology spike sorting
bioRxiv · 5 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.06.20.660590
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