Research area · week to 3 Oct 2026

Cardiac Valve Diseases and Treatments

Moving in medRxiv, bioRxiv, New England Journal of Medicine, Circulation.

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Latest in Cardiac Valve Diseases and Treatments

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Metabolic Perturbation Exacerbates Sinoatrial Node Dysfunction in Heart Failure
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.06.704519
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Stromal CTHRC1 protects the valvular interstitium from macrophage-associated inflammatory remodeling and calcification
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.21.753362
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Machine Learning identification in patients with aortic valve stenosis of a myocardial miRNA signature predictive of reverse cardiac remodelling after valve replacement
medRxiv · 24 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.22.26363736
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Altered kynurenine and indole tryptophan pathways in calcific aortic stenosis: cross-sectional evidence for a gut-host metabolic imbalance (GUT-CAS)
medRxiv · 16 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.22.26353844
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Advancing Quality in the Evaluation, Surveillance, and Management of Aortic Stenosis: A Report From the AHA Target: AS Registry.
Circulation · 8 Sept 2026 · Multicenter Study
Timely diagnosis and treatment of aortic stenosis improved modestly from 2023 to 2024 but remain suboptimal, with only 54-61% diagnosed within 30 days at a national level.
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https://jclub.com.au/a/42360276
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WITHDRAWN: Perspectives of Interventional Cardiologists and Cardiothoracic Surgeons on the Late Diagnosis and Undertreatment of Women Diagnosed with Severe Symptomatic Aortic Stenosis
medRxiv · 2 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.29.26345174
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Timing of PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.
New England Journal of Medicine · 30 Aug 2026 · Journal Article
Performing TAVI before PCI is noninferior to PCI before TAVI regarding 1-year outcomes in patients with severe aortic stenosis and coronary artery disease, with a 22.2% versus 24.2% event rate.
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https://jclub.com.au/a/42670987
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Tricuspid-Valve Intervention in Heart Failure.
New England Journal of Medicine · 30 Aug 2026 · Journal Article
Transcatheter tricuspid-valve repair significantly reduces death and hospitalization risks in patients with severe tricuspid regurgitation, with a win ratio of 2.42 at 1 year.
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https://jclub.com.au/a/42670975
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Deep Learning-Based Single-View Echocardiographic Analysis for Prediction of Left Ventricular Outflow Tract Gradient Elevation After Transcatheter Aortic Valve Replacement
medRxiv · 24 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.27.26349567
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