Quantitative proteomics uncovers a role for REVEILLE8-like clock genes in osmotic and salt stress response in Arabidopsis.

Loss of Arabidopsis RVE4, RVE6, and RVE8 substantially alters proteome regulation for osmotic stress, photosynthesis, and phenylpropanoid metabolism, especially at end-of-day.

• Why it matters: Circadian clock genes are linked to daily timing of stress responses, but proteome-level mechanisms for RVE8-like regulators under osmotic and salt stress remain unclear.
• What they did: Using quantitative proteomics, the study compared rve4 6 8 plants to controls at end-of-day and end-of-night timepoints under osmotic and salt stress.
• The result: The data identify end-of-day protein changes and new drought-responsive targets affected by RVE4, RVE6, and RVE8, implicating fatty acid metabolism and abscission.

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