The abstract is read at the publisher; the summary is JClub's.
A stable genotype-phenotype map in Drosophila melanogaster predicts the direction of pigmentation evolution, but the specific selected loci remain largely unpredictable.
- Why it matters: It is unclear whether genomic data can forecast how complex traits adapt in natural populations, especially when genotype-phenotype relationships appear stable.
- What they did: The study tracked genome-wide allele frequencies and pigmentation variation in genetically diverse Drosophila melanogaster across field mesocosms and a controlled lab setting, using a high-powered genotype-phenotype map at two stages.
- The result: The map correctly inferred pigmentation evolution direction in both environments, yet loci under selection were largely unpredictable from the trait’s evolutionary direction, limiting genomic prediction.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.