The abstract is read at the publisher; the summary is JClub's.
Community science air sampling across Norway found azole-resistant Aspergillus fumigatus in 15 isolates (0.95%) from 14 locations, including a novel TR(62) tandem repeat variant.
- Why it matters: Northern Europe lacks nationwide baseline data on environmental azole resistance, limiting monitoring of antifungal resistance that can spread through airborne spores.
- What they did: Volunteers collected spores using passive sticky-seal traps in 2,332 air samples from 398 locations (2022–2023), followed by azole screening, MIC confirmation, and whole-genome sequencing.
- The result: Resistance mechanisms included TR34/L98H (n=11), TR46/Y121F/T289A (n=2), and a TR46/Y121F/T289A/S363P/I364V/G448S variant (n=1), with TR(62) in one multi-azole resistant isolate.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.