Burst-to-burst information resetting in sequential rhythmic neural activity.

Cycle-by-cycle coordination in the pyloric CPG is governed by burst-onset and burst-offset interval variability, with sequential dynamical invariants that either reset each cycle or persist across consecutive cycles.

• Why it matters: Robust sequential rhythms require reliable timing relationships, but it is unclear when coordination constraints remain stable versus when they reset from one cycle to the next.
• What they did: The authors combined electrophysiology with biophysical modeling of the pyloric CPG, analyzing how interval variability constraints shape relationships among specific within-cycle intervals.
• The result: They identified conditions producing robust sequential dynamical invariants as relationships between intervals in the same cycle, and conditions where those relations reset each cycle or extend across consecutive cycles under slow modulation.

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