The abstract is read at the publisher; the summary is JClub's.
In 6 Australian public hospitals, a stepped-wedge trial in patients aged 65+ with DBI>0 found only a modest, less-than-expected increase in deprescribing at discharge.
- Why it matters: Anticholinergic and sedative drugs are linked to poor outcomes in older inpatients, but evidence-based deprescribing strategies are still needed.
- What they did: From January 2022 to July 2023, study stewardship pharmacists promoted an informational DBI bundle in the intervention phase, while the informational component alone ran in control and sustainability phases.
- The result: Deprescribing of at least one DBI-contributing medication occurred in 41.4% (326/788) vs 38.1% (788/2069) in control (aAD 5.3 percentage points, 95% CI 0.1-10.6), and the effect was not sustained after stewardship ended.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.