The abstract is read at the publisher; the summary is JClub's.
SNP544 C/G in the MdWRKY11 promoter is the major determinant of Glomerella leaf blotch susceptibility in apple, with the G allele linked to 96.2% prediction accuracy.
- Why it matters: Markers exist for GLB susceptibility in apple, but the causal functional variation driving the dominant susceptibility locus remained unclear.
- What they did: Using MapQTL and fine mapping, the study identified SNP544 C/G in MdWRKY11; the G allele creates a W-box bound by MdWRKY29 that activates MdWRKY11 during Colletotrichum gloeosporioides infection.
- The result: MdWRKY11 then activates MdDMR6.1, associated with salicylic acid degradation and leaf necrosis, and MdWRKY11 allelic variation across 29 accessions yields 99.6% combined prediction accuracy for GLB susceptibility.
The findingWhy it mattersWhat they didThe result
AI summary of the abstract · may contain errors · not medical advice · read the paper.