The abstract is read at the publisher; the summary is JClub's.
Rhg1-encoded atypical SNAP18LC/HC variants promote ATG8-dependent selective autophagic degradation of the soybean cyst nematode effector HgGID, neutralizing its virulence function.
- Why it matters: Rhg1 resistance against Heterodera glycines is known, but how its SNAP18 proteins restrict an evolutionarily advanced nematode effector has remained unclear.
- What they did: Using TurboID proximity labeling, the study found HgGID associates with SNAP18 and co-enriches ubiquitin-proteasome and SNARE-associated factors; SNAP18LC/HC variants increase HgGID AIM accessibility and drive ATG8-dependent selective degradation.
- The result: Targeted autophagic clearance efficiently neutralizes HgGID’s virulence activity, supporting a suicide-bait immune-trap paradigm for plant defense against metazoan pathogens.
The findingWhy it mattersWhat they didThe result
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