FEMS Microbio LettersJClub
CircoTax: a novel circular representation of differentially abundant microbial ranks.
FEMS microbiology letters · · Journal Article
Casbarra, Di Gloria + 1 more
Abstract ↗AI summary
The abstract is read at the publisher; the summary is JClub's.
CircoTax provides a rank-aware circular R ggplot2 visualization that compactly displays differentially abundant microbial taxa across phylum-to-genus sectors using log2 fold-change direction and p-value.
- Why it matters: Existing NGS differential abundance methods report taxa with adjusted p-values and log2 fold changes, but results can be hard to interpret when many taxonomic ranks are involved.
- What they did: CircoTax draws a radial plot where sectors encode taxonomy depth (phylum to genus) and radial bars extend to rank-based sectors colored and transparent by log fold-change intensity direction and p-value.
- The result: The approach supports tens of differentially abundant ranks with up/down variation in a glanceable format, and is available as an R package or via a ShinyApp.
The findingWhy it mattersWhat they didThe result
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