PanGBank: a large-scale resource of precomputed microbial pangenomes built with PPanGGOLiN.

PanGBank provides precomputed pangenomes for over 4600 prokaryotic species, covering more than 393,000 genomes, enabling large-scale comparative genomics.

• Why it matters: It addresses the need for a standardized, accessible resource to explore microbial diversity, genome evolution, and functional variation across broad taxonomic scales.
• What they did: The database was built using PPanGGOLiN partitioned pangenome graphs and includes two collections: GTDB_all and GTDB_refseq, with integrated gene families, regions of genomic plasticity, and functional modules.
• The result: PanGBank offers multiple access modes and supports analyses like investigating antimicrobial resistance in Acinetobacter baumannii, facilitating insights into microbial adaptive traits.