Toward a shared infrastructure for preclinical discovery: Why animal model tissue and biofluid biobanks are needed.

Standardized biobanks of animal model tissues and biofluids could transform preclinical research by enhancing reproducibility and reducing animal use.

• Why it matters: Current preclinical studies often underutilize available biological samples, leading to duplicated efforts and inconsistent results, which hinder biomarker development and translation.
• What they did: The authors advocate for establishing shareable, standardized biobanks of animal tissues and biofluids, emphasizing their potential to streamline research and foster collaboration across sectors.
• The result: Implementing such biobanks would decrease redundant experiments, improve data reliability, and create scalable infrastructure that benefits both academic and industrial preclinical efforts.