Intra-Arterial Tenecteplase After Endovascular Thrombectomy for Acute Stroke: One-Year Outcomes of the ANGEL-TNK Randomized Clinical Trial.

Intra-arterial tenecteplase improves 12-month outcomes after endovascular thrombectomy in acute stroke patients, as shown in the ANGEL-TNK trial.

• Why it matters: Understanding long-term benefits of adjunctive treatments can enhance stroke recovery strategies and patient prognosis, filling a critical knowledge gap in post-thrombectomy care.
• What they did: The study analyzed 12-month outcomes from a randomized trial involving patients who received intra-arterial tenecteplase alongside endovascular thrombectomy, assessing its efficacy over a year.
• The result: Findings suggest that intra-arterial tenecteplase may significantly improve long-term functional recovery, supporting its potential as a beneficial adjunct in stroke treatment protocols.