Nature Immunology · 22 Sept 2026 · Letter

Updating the symbols of ten cytokines and their receptors: report of the IUIS Cytokine Nomenclature Sub-Committee.

Boraschi, Dong + more

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Unexpected functional role of the transactivation domain for nuclear import of STAT5.
Communications Biology · 26 Sept 2026 · Journal Article
The transactivation domain (TAD) is essential for nuclear import of phosphorylated STAT5, with two key residues D754 and D758 critical for this process.
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Refining therapeutic targeting of interleukin-6 by signalling mode selectivity.
Nature Reviews Drug Discovery · 23 Sept 2026 · Review
Selective targeting of IL-6 trans-signalling pathway offers potential for safer, more precise therapies, as it accounts for distinct roles in disease and homeostasis.
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Structural basis of context-dependent RORγt target gene activation on chromatin
bioRxiv · 17 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.03.10.642251
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